Archive for the ‘Stem Cell Industry’ Category

Nov 28, 2012

Can Dog Paralysis be Cured by Regenerative Medicine?

Posted by Bob under Dog Stem Cells, Stem Cell Industry

I am guessing that you might have heard about the exciting data about dogs with damaged spinal cords that were treated with regenerative medicine. As with all science, the devil is in the details.  Cure is a BIG concept.  The group in England presented data in the journal  Brain showing that a stem-like cell from the nervous tissue in the nose could be injected in the damaged spinal cord of dogs.  These cells apparently helped make connections between the rear and front feet to allow a more coordinated walking movement.  It is difficult to see from the single video (this might have been the best one) to tell how much the dogs were helped.  They do state that the dogs did not regain bowel or bladder control. This study was for the purpose of deciding if this therapy could some day help humans. For us, we are excited because it may help our four legged friends.

The dog in the video improved over six months to be able to walk with the hind legs mostly following the front.  It is a major advance, but far from a cure for paralysis.  The authors are realistic in stating: “..this intervention alone is unlikely to have appreciable benefits in the treatment of human spinal cord injury…”  The therapy helps the rear legs follow the front legs without re-connecting to the brain.  It would not likely help with the more complicated activities such as bladder control, hand motion, or sexual function.

Another interesting possibility presented by the authors is that “the precise type of cells in the transplant is not critical to the success of mucosal-derived transplants.”  Vet-Stem is exploring with the authors whether adipose stem cells might provide a similar benefit, as was shown in an article by Dr. Ryu (click here for link).

Science always brings hope, but it is important to realize the time lag of translating clinical trial data into real therapy for affected animals or humans.  We will update you as we determine if this method might be useful to our dog buddies in the near term.

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Oct 22, 2012

Human Crohn’s Disease Trial Reports

Posted by Bob under dog arthritis, Stem Cell Industry

Human stem cell therapy succeeds!  As part of providing insights into the world of dog arthritis, I think it is useful for you to see what all is happening in the human stem cell world.  Crohn’s disease is a horrible auto-immune disease where the lower GI tract is being attacked by the person’s own immune system.  A group in Spain has been working for a number of years treating patients with this disease with adipose stem cell therapy.  There is a great report of clinical trial you should all see (link: Crohn’s Trial Results) where more than half of these patients had a great response to being treated with adipose stem cells.  There are so many new trials around the world using stem cell from fat tissue that it is hard to keep up with the literature.  Proudly, I believe that the success with using adipose stem cells to treat dog arthritis, like Tucker’s Story,  has helped generate interest and to show the safety of this type of therapy.

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Dec 1, 2011

Global Leaders in Stem Cell Therapy Meet in La Jolla

Posted by Bob under Stem Cell Industry

Yesterday a global stem cell meeting began in La Jolla with leaders from around the world, “Stem Cells on the Mesa.”  The discussions are centered on stem cell science and the development of new products.  Vet-Stem presented the stem cell story in veterinary medicine to the amazement of many in the audience.  Researchers and business leaders commented that Vet-Stem and veterinary medicine were leaders in translating stem cell science into true clinical treatments.  With over 4000 horses and 4000 dogs treated with stem cells, we are helping the industry see that stem cell therapy really works and is safe! Read the rest of this entry »

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